http://www.nature.com/ijo/journal/v24/n4/pdf/0801185a.pdf

In this study we evaluated the effects of two low-energy diets (balanced and dissociated) on both weight loss (total and fat body weight) and various metabolic parameters. The amount of weight loss was similar in response to the two diets (which had similar energy and macronutrients contents (Table 2)) and was apparently independent of the substrate distribution within meals, being principally related to total energy intake, in accordance with previous works from our group and others.
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